Cure for Cade
Help fund gene therapy and give Cade a brighter Future
Upcoming Fundraising Events
Concert for Cade
Saturday July 20th
Tillet Gardens
St. Thomas VI
Walkathon
Saturday September 7th
Mendenhall Mall
Juneau AK
Cade’s Story
Cade Jobsis is 3 years old and has been the happiest kid who brings joy to everyone he meets, but he has always fallen behind his peers in meeting milestones. In the summer of 2023, we participated in a genetic sequencing study with hopes that it would shed light on Cade’s slow progress. The tests revealed that he was born with an ultra-rare genetic disease called AP4 Hereditary Spastic Paraplegia(SPG50). We were devastated to learn that the disease is degenerative and without treatment will progress to a loss of motor and cognitive function. We will do everything in our power to defy the odds and ensure a different future for our son.
In the depths of our despair there is hope. Cade’s disorder can now be treated with a new gene therapy, however the program responsible for putting together the clinical trials has recently fallen short of the funding needed. In an effort to ensure he gets the treatment he desperately needs, we
are doing everything we can to raise the funds.
As we are swallowed by grief, our only comfort is found in Cade who is still the happiest child we know. We live for his smile. It reminds us every day of how lucky we are to be his parents. To save Cade and other children sharing his condition, they need to get treatment as soon as possible due to the degenerative nature of the disease. Their only obstacle is funding. The medicine they need already exists.
Your generosity can make a significant difference in our efforts to access this life-changing gene therapy. You can contribute directly through Venmo or our GoFundMe page, linked below for your convenience. For those seeking a tax-deductible option, donations can also be made through Jacks Corner Foundation, a registered non-profit 501(c)(3) organization dedicated to supporting healthcare advancements for kids with SPG50. Your support, in any form, brings us closer to achieving our goal and offering hope to those in need. Thank you for considering our cause and for your kindness in advance.
Thank all you for your love and support. We can’t do this without you!
Fund a Cure for Cade
GoFundMe or Venmo
Jack’s Corner Foundation
Non-Profit Organization
- Funds Gene Therapy Treatment
- Funds research to develop additional treatment and cures
- Spreads Awareness
Cure SPG50
Non-Profit Organization
- Funds the development of treatment for SPG50 and supports families affected by the disease.
More Information
About US
We are a family that came from unlikely circumstances. Emma is from Alaska and Dylan the Caribbean. We decided to start a family in the midst of the 2020 pandemic and had Cade in the spring of 2021. If you are dealing with an AP-4 diagnosis, please don’t hesitate to contact us. We would be happy to guide you through what we know as other families did for us.
Therapy and Treatments
Cade participates in traditional physical, speech, and occupational therapy. We also hope to do some intensive therapy in the future but this is quite expensive. We are exploring options for experimental treatments but Cade’s best option for treatment at the moment is the clinical trial of gene therapy
What is SPG50?
SPG50 is an ultra-rare degenerative genetic neurological disorder caused by the inheritance of two faulty copies of the AP4M1 gene. This gene codes for one of four subunits in the AP4 complex which is thought to be involved in autophagy, a critical cellular function.
Links to More Information
Grandmas Corner
Cade has two incredible grandmas who want to help. If you are interested in ordering a stained glass piece or dahlia tubers, consider sending them a message.
Glass by Rosalyn
Contact Rosalyn Rossignol
rosrossignol@gmail.com
Grandma’s Garden
Contact Beth Landvatter
landvatter@gmail.com
WE LIVE FOR THESE SMILES
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Contact US
@cureforcade
cureforcade@gmail.com